Topical Undecylenic Acid for Herpes Simplex Labialis: A Multicenter, Placebo‐Controlled Trial
نویسندگان
چکیده
منابع مشابه
Recurrent herpes simplex labialis: selected therapeutic options.
Recurrent infection with herpes simplex virus 1 (HSV1), called herpes simplex labialis (HSL), is a global problem for patients with normal immune systems. An effective management program is needed for those with frequent HSL recurrences, particularly if associated morbidity and life-threatening factors are present and the patient's immune status is altered. Over the past 20 years, a variety of ...
متن کاملCombined herbal preparation for topical treatment of Herpes labialis.
BACKGROUND The efficacy of many preparations for topical use in herpes infections have remained rather disappointing. The development of new antiviral drugs, especially herbal preparations, thus remains desirable. In a screening study with plant extracts, a rhubarb root extract and a sage extract showed a promising activity. OBJECTIVE The efficacy of a combined topical preparation with rhubar...
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Because deficient immune responses may play a contributory role in recurrent herpes simplex labialis, an immunomodulating agent, levamisole, has been advocated for therapy. Forty-two patients with a high frequency of recurrent herpes simplex labialis were followed for a mean of 7.8 months (range 4 to 12) and treated for 3 days at the onset of each episode of herpes with one of three different d...
متن کاملSurveillance for antiviral-agent-resistant herpes simplex virus in the general population with recurrent herpes labialis.
In a general population survey in the United States, the prevalence of antiviral-agent-resistant herpes simplex virus was very low among more than 1,000 isolates from individuals with an episode of recurrent herpes labialis not treated with topical antiviral agents. Two isolates had borderline resistance to acyclovir (0.2%), and all were susceptible to penciclovir.
متن کاملSuccessful treatment of herpes labialis with topical acyclovir.
A double blind, placebo controlled trial of 5% acyclovir cream, applied topically five times a day for five days, was carried out in 49 patients with recurrent herpes labialis. These patients had a total of 74 episodes, 34 of which were treated with the 5% acyclovir cream and 40 with matching placebo. First episodes and all episodes treated with acyclovir cream had significantly shorter times t...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 1997
ISSN: 0022-1899,1537-6613
DOI: 10.1086/514042